# To reproduce the data needed for Figure 13 in associated original paper, # execute this script in the Python console in OpenCOR. This can be done # with the following commands at the prompt in the OpenCOR Python console: # # In [1]: cd path/to/folder_this_file_is_in # In [2]: run originalFig13_sim.py import opencor as oc import get_init import imp imp.reload(get_init) # The prefix of the saved output file name prefilename = 'simFig13' # Load the simulation file simfile='periodic-stimulus.sedml' simulation = oc.open_simulation(simfile) # The data object houses all the relevant information # and pointers to the OpenCOR internal data representations data = simulation.data() # Define the interval of interest for this simulation experiment start, end, pointInterval = 0, 20, 0.001 data.set_starting_point(start) data.set_ending_point(end) data.set_point_interval(pointInterval) # Compute initial value based on T and V_b T, V_b = 6, 0 m, n, h = get_init.init_gate(T, V_b) V_initial = [-15] for i, iV_initial in enumerate(V_initial): filename ='%s_(%d)mV.csv' % (prefilename, iV_initial) # Reset states and parameters simulation.reset(True) # Set constant parameter values data.states()['outputs/V'] = iV_initial data.constants()['parameters/T'] = T data.states()['outputs/m'] = m data.states()['outputs/n'] = n data.states()['outputs/h'] = h simulation.run() # Access simulation results results = simulation.results() # Access the full datastore representation of the simulation results ds = results.data_store() voi_and_variables = ds.voi_and_variables() # Save the simulation result outfile = open(filename, 'w') cols = [] for key, item in voi_and_variables.items(): outfile.write(str(key) + ",") cols.append(list(item.values())) outfile.write("\n") for i in range(0, len(cols[0])): for j in range(0, len(cols)): outfile.write(str(cols[j][i]) + ",") outfile.write("\n") outfile.close() # clear the results simulation.clear_results()