Nickerson David david.nickerson@nus.edu.sg National University of Singapore Division of Bioengineering 2007-06-20 Division of Bioengineering, National University of Singapore Various modifications for INaCa due to ischemic effects. Doering and Lederer (1993) based formulation of pHi dependence of INaCa. guinea pig Ventricular Myocyte 8410703 Doering A E Lederer W J The mechanism by which cytoplasmic protons inhibit the sodium-calcium exchanger in guinea-pig heart cells. 1993 J Physiol 466 481 499 Haworth and Goknur (1992) based formulation of [ATP]i dependence of INaCa. rat 1606663 Haworth R A Goknur A B ATP dependence of calcium uptake by the Na-Ca exchanger of adult heart cells. 1992 Circ. Res. 71 1 210 217 Modified INaCa current taking intracellular pH and [ATP]i into account. $\mathrm{INaCa}=\mathrm{pHi}\mathrm{ATPi}\mathrm{INaCa\_original}$