I_stim stim_a t t stim_p stim_p stim_s t t stim_p stim_p stim_s stim_d 0 t V I_K1 I_to I_Kr I_Ks I_CaL I_CaT I_NaK I_Na I_bNa I_NaCa I_bCa I_pK I_pCa I_f I_stim E_Na R T F Na_e Na_i E_K R T F K_e K_i E_Ks R T F K_e P_KNa Na_e K_i P_KNa Na_i E_Ca 0.5 R T F Ca_e Ca_i I_Na g_Na m 3 h j V E_Na m_inf 1 1 56.86 V 9.03 2 alpha_m 1 1 60 V 5 beta_m 0.1 1 V 35 5 0.1 1 V 50 200 tau_m 1 alpha_m beta_m t m m_inf m tau_m h_inf 1 1 V 71.55 7.43 2 alpha_h 0.057 V 80 6.8 V 40 0 beta_h 2.7 0.079 V 310000 0.3485 V V 40 0.77 0.13 1 V 10.66 11.1 tau_h 1 alpha_h beta_h t h h_inf h tau_h j_inf 1 1 V 71.55 7.43 2 alpha_j 25428 0.2444 V 6.948-6 0.04391 V V 37.78 1 0.311 V 79.23 V 40 0 beta_j 0.02424 0.01052 V 1 0.1378 V 40.14 V 40 0.6 0.057 V 1 0.1 V 32 tau_j 1 alpha_j beta_j t j j_inf j tau_j alpha_K1 0.1 1 0.06 V E_K 200 beta_K1 3 0.0002 V E_K 100 0.1 V E_K 10 1 0.5 V E_K xK1_inf alpha_K1 alpha_K1 beta_K1 I_K1 g_K1 xK1_inf K_e 5.4 V E_K I_Kr g_Kr K_e 5.4 Xr1 Xr2 V E_K xr1_inf 1 1 26 V 7 alpha_xr1 450 1 45 V 10 beta_xr1 6 1 V 30 11.5 tau_xr1 1 alpha_xr1 beta_xr1 t Xr1 xr1_inf Xr1 tau_xr1 xr2_inf 1 1 V 88 24 alpha_xr2 3 1 60 V 20 beta_xr2 1.12 1 V 60 20 tau_xr2 1 alpha_xr2 beta_xr2 t Xr2 xr2_inf Xr2 tau_xr2 I_Ks g_Ks Xs 2 V E_Ks xs_inf 1 1 5 V 14 alpha_xs 1400 1 5 V 6 beta_xs 1 1 V 35 15 tau_xs 1 alpha_xs beta_xs 80 t Xs xs_inf Xs tau_xs I_CaL g_CaL d f f2 fCaSS 4 V 15 F 2 R T 0.25 Ca_SS 2 V 15 F R T Ca_e 2 V 15 F R T 1 d_inf 1 1 8 V 7.5 alpha_d 1.4 1 35 V 13 0.25 beta_d 1.4 1 V 5 5 gamma_d 1 1 50 V 20 tau_d 1 alpha_d beta_d gamma_d t d d_inf d tau_d f_inf 1 1 V 20 7 tau_f 1102.5 V 27 2 225 200 1 13 V 10 180 1 V 30 10 20 t f f_inf f tau_f f2_inf 0.67 1 V 35 7 0.33 tau_f2 562 V 27 2 240 31 1 25 V 10 80 1 V 30 10 t f2 f2_inf f2 tau_f2 fCaSS_inf 0.6 1 Ca_SS 0.05 2 0.4 tau_fCaSS 80 1 Ca_SS 0.05 2 2 t fCaSS fCaSS_inf fCaSS tau_fCaSS I_CaT g_CaT d_T f_T V E_Ca 75 d_Tinf 1 1 23 V 6.1 tau_d_T 0.6 5.4 1 0.03 V 100 t d_T d_Tinf d_T tau_d_T f_Tinf 1 1 V 75 6.6 tau_f_T 1 40 1 0.08 V 65 t f_T f_Tinf f_T tau_f_T I_NaCa k_NaCa gamma V F R T Na_i 3 Ca_e gamma 1 V F R T Na_e 3 Ca_i alpha Km_Nai 3 Na_e 3 Km_Ca Ca_e 1 K_sat gamma 1 V F R T I_NaK p_NaK K_e K_e K_mk Na_i Na_i K_mNa 1 0.1245 0.1 V F R T 0.0353 V F R T I_to g_to r s V E_K s_inf 1 1 V 20 5 tau_s 85 V 45 2 320 5 1 V 20 5 3 t s s_inf s tau_s r_inf 1 1 20 V 6 tau_r 9.5 V 40 2 1800 0.8 t r r_inf r tau_r g_fNa 0.5949 g_fK I_fNa g_fNa y V E_Na I_fK g_fK y V E_K I_f I_fNa I_fK y_inf 0.01329 0.99921 1.0 V 97.134 8.1752 V 80.0 0.0002501 V 12.861 tau_y 1.0 0.00036 V 148.8 0.066 V 148.8 1.0 0.0001 V 87.3 1.0 0.2 V 87.3 54 t y y_inf y tau_y I_pK g_pK V E_K 1 25 V 5.98 I_pCa g_pCa Ca_i Ca_i K_pCa I_bNa g_bNa V E_Na I_bCa g_bCa V E_Ca t Na_i I_Na I_fNa I_bNa 3 I_NaK 3 I_NaCa V_c F C_m t K_i I_K1 I_to I_Kr I_Ks I_fK I_pK I_stim 2 I_NaK V_c F C_m I_rel a_RyR V_rel O Ca_SR Ca_SS I_up a_SERCA Vmax_up 1 K_up 2 Ca_i 2 I_leak a_RyR V_leak Ca_SR Ca_i I_xfer V_xfer Ca_SS Ca_i O k1 Ca_SS 2 R_prime k3 k1 Ca_SS 2 t R_prime k2 Ca_SS R_prime k4 1 R_prime k1 k1_prime kcasr k2 k2_prime kcasr kcasr max_SR max_SR min_SR 1 EC Ca_SR 2 Ca_i_bufc 1 1 a_TropC Buf_c K_buf_c Ca_i K_buf_c 2 Ca_SR_bufSR 1 1 a_CASQ Buf_SR K_buf_SR Ca_SR K_buf_SR 2 Ca_SS_bufSS 1 1 a_TropC Buf_SS K_buf_SS Ca_SS K_buf_SS 2 t Ca_i Ca_i_bufc I_leak I_up V_SR V_c I_xfer I_bCa I_pCa 2 I_NaCa C_m 2 V_c F t Ca_SR Ca_SR_bufSR I_up I_rel I_leak t Ca_SS Ca_SS_bufSS I_CaL I_CaT C_m 2 V_SS F I_rel V_SR V_SS I_xfer V_c V_SS